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• Front Matter
• NOVEL DRUG CARRIERS AND THERAPEUTICS. Nanoarchitectured Materials / Moreshwar P Patil, Lalita S Nemade
• Nanopharmaceuticals for Drug Delivery / Swapnali Ashish Patil, Akshadha Atul Bakliwal, Vijay Sharad Chudiwal, Swati Gokul Talele
• Applications and Prospects of Nanopharmaceuticals Delivery / Hemant K S Yadav, Fejer Al mohammedawi, Rawan J I Abujarad
• Nanomedicine Regulation and Future Prospects / R Md Anwar Nawaz, G I Darul Raiyaan, K Sivakumar, Kantha D Arunachalam
• Nanotechnology Application in Drug Delivery for Medicinal Plants / Bui Thanh Tung, Duong Van Thanh, Nguyen Phuong Thanh
• Nanosystems Trends in Nutraceutical Delivery / Aristote Buya
• Nanoencapsulated Systems for Delivery of Phytopharmaceuticals / Jacqueline Renovato-Núñez, Luis Enrique Cobos-Puc, Ezequiel Viveros-Valdez, Anna Iliná, Elda Patricia Segura-Ceniceros, Raúl Rodríguez-Herrera, Sonia Yesenia Silva-Belmares
• Topical Drug Delivery Using Liposomes and Liquid Crystalline Phases for Skin Cancer Therapy / Karina Alexandre Barros Nogueira, Jéssica Roberta Pereira Martins, Thayane Soares Lima, Jose Willams Bandeira Alves Junior, Alanna Letícia Carmo Aquino, Lorena Maria Ferreira Lima, Josimar O Eloy, Raquel Petrilli
• Vesicular Drug Delivery in Arthritis Treatment / Nilesh Gorde, Sandeep O Waghulde, Ajay Kharche, Mohan Kale
• Perspectives of Novel Drug Delivery in Mycoses / D Maheswary, Kakithakara Vajravelu Leela, Sujith Ravi
• Nano-Based Drug Delivery in Eliminating Tuberculosis / Anusha Gopinathan, Shweta Sagar Naik, KV Leela, Sujith Ravi
• Promising Approaches in Drug Delivery Against Resistant Bacteria / Shweta Sagar Naik, G Anusha, Kakithakara Vajravelu Leela, Sujith Ravi
• Emulgels / Shanti Bhushan Mishra, Shradhanjali Singh, Amit Kumar Singh, Anil Kumar Singh, Divya Rani Sharma
• Electrospun Nanofibers in Drug Delivery / Sathish Kumar Karuppannan, Saravannan Mani, Jayandra Bushion, Mohammed Junaid Hussain Dowlath, Kantha Deivi Arunachalam
• DRUG CARRIERS IN DRUG DELIVERY. Role of Nanotechnology-Based Materials in Drug Delivery / R Manasa, Mahesh Shivananjappa
• Nanomedicine Drug Delivery System / Akshada Atul Bakliwal, Swapnali Ashish Patil, Vijay Sharad Chudiwal, Swati Gokul Talele, Gokul Shravan Talele, Anil Govindrao Jadhav
• Nanocarriers-Based Topical Formulations for Acne Treatment / Júlia Scherer Santos
• Emerging Trends of Ocular Drug Delivery / Sora Yasri, Viroj Wiwanitkit
• Microspheres / Sarang Kumar Jain, Swati Saxena, Raj K Keservani
• Drug Delivery Systems and Oral Biofilm / Elda Patricia Segura Ceniceros, Luis Méndez González, Reginaldo Tijerina, Eduardo Osorio Ramos, Francisco Javier Mendoza González, Verónica Leticia Rodríguez Contreras, Alejandra Isabel Vargas Segura, Luis Antonio Vázquez Olvera
• Oral Drug Delivery System / Sarang Kumar Jain, Ankita Sahu, Raj K Keservani
• Cancer Nanotheranostics / Ozge Esim, Canan Hascicek
• Nanomedicine in Lung Cancer Therapy / C Jagdale Swati, A HableAsawaree, R ChabukswarAnuruddha
• Delivering Herbal Drugs Using Nanotechnology / R Manasa, Mahesh Shivananjappa
• Nanoherbals Drug Delivery System for Treatment of Chronic Asthma / Harsh Yadav, Satish Dubey, Naureen Shaba Khan, Ashwini Kumar Dixit
• Nutrients Delivery for Management and Prevention of Diseases / G I Darul Raiyaan, A Sameera Khathoon, Kantha D Arunachalam
• Nanonutraceuticals for Drug Delivery / Charu Gupta, Dhan Prakash
• Index

• Antibody-Drug Conjugates Basic Concepts and Structures
• Relationship between target and specific action of antibody-drugs conjugates
• The internalization and therapeutic activity of antibody drug conjugate
• The internalization and intracellular trafficking of ADC
• Distribution and metabolism of antibody-drug conjugates
• Application of Antibody fragments in ADCs
• Novel Targeting Carriers in Antibody-drug Conjugates
• Site-specified Conjugating Technology and Application
• Determination of drug-to-antibody ratio of ADCs
• Pharmacokinetic study of antibody-drug conjugates.

This book summarizes the related research achievements in Antibody-drug conjugates (ADCs) and their cell metabolism kinetics. The book has three main parts. The first part describes the basic theory of ADCs, including the basic concept and structure of ADCs, and the relationship between the targets of ADCs and their specific functions. The second part mainly introduces the endocytosis and intracellular metabolism of ADCs, including the relationship between endocytosis and ADC activity, the endocytosis and intracellular transport of ADCs, the distribution and metabolism of ADC in vivo. Then it discusses the new formats and research technology of ADCs, including the application of miniaturized antibodies in ADC synthesis, novel carriers for ADC design, the technology and application of site-specific conjugation, and approaches for analyzing the drug: antibody ratio (DAR), the study of pharmacokinetics of ADCs. This book combines the basic theory with the research technology. It can be used as a reference book for students, teachers and researchers of biomedical field.

• 1. Historical developments of antimicrobial peptide research
• 2. Biosynthesis of peptide antibiotics and innate immunity
• 3. Antimicrobial peptides: features and mode of action
• 4. Purification techniques and characterisation of antimicrobial peptides
• 5. Peptide antibiotics from bacteria
• 6. Antimicrobial peptides of fungal origin
• 7. Insect peptides with antimicrobial effect
• 8. Amphibian host defence peptides
• 9. Plant derived antimicrobial peptides
• 10. Mammalian antimicrobial peptides
• 11. Antimicrobial peptides from marine environment
• 12. Peptides with antiviral activities
• 13. Peptide antibiotics against MDR bacteria
• 14. Antimicrobial peptide resistance
• 15. Recent advances and challenges in peptide drug development
• 16. Future perspective of peptide antibiotic market.
• (source: Nielsen Book Data)

Antimicrobial Peptides: Challenges and Future Perspectives covers the latest developments about antimicrobial peptides in the scenario of drug resistance. The book is divided into 16 chapters arranged in sequence and preceded by chapters on historical developments and their role as regulatory molecules in innate defense mechanism. Emphasis is given to purification techniques and characterization suitable for interdisciplinary research. Chapters provide an inventory of various antimicrobial peptides, from a diverse array of organisms such as bacteria, fungi, insects, amphibians, plants and mammals. A section on marine ecosystem broadens readers understanding on marine based antimicrobial peptides. Additional sections provide an informative overview on peptides with antiviral properties and those targeting multi-drug resistant bacteria. Recent reports and mechanism on resistance against antimicrobial peptides are also provided, along with key insights into the challenges and future perspectives of peptide drug development.
(source: Nielsen Book Data)

For centuries, Chinese medicinal materials have been used for therapeutic purposes. Chinese medicinal materials are traditionally identified by their organoleptic characteristics, such as the texture or the odor. With the advancement of DNA technology, a molecular approach has become an important tool to complement organoleptic, morphological, anatomical and chemical techniques for the authentication and quality assurance of Chinese medicinal materials.In 2002, the authors published Authentication of Chinese Medicinal Materials by DNA Technology which is the first international reference in this field. After 20 years, this new edition updates the various useful techniques and describes the new techniques developed for molecular authentication. The procedures of each DNA technique are provided in detail for 'step-by-step' experiments.This book is divided into 5 parts with 18 chapters. Part I reviews the current status of molecular authentication and introduces a wide range of DNA techniques. Part II lists the experimental procedures for molecular authentication. Part III describes the DNA fingerprinting-based techniques. Part IV describes the DNA sequencing-based techniques. Finally, Part V provides an account on the recent advancement in molecular authentication, including guidelines for setting up a proper DNA laboratory and concluding remarks.
(source: Nielsen Book Data)

• Chronology
• Abbreviations
• Preface and acknowledgements
• 1. Introduction
• 2. l-Physostigmine (eserine)
• 3. l-Physovenine
• 4. l-Eseramine
• 5. l-N(8)-Norphysostigmine
• 6. l-Geneserine
• 7. 1H-, 13C- and 15N-Nuclear magnetic resonance spectra of the alkaloids of the Calabar bean
• 8. Other alkaloids of, as yet, unknown structures that have been isolated, or allegedly so, from the Calabar bean
• 9. Non-alkaloidal components of the Calabar bean
• 10. Biological activities of the alkaloids of the Calabar bean
• 11. Notes
• 12. References
• 13. Index.

Investigations into Calabar beans (the dried ripe seeds of Physostigma venenosum) and their alkaloidal components compose a classical scientific journey throughout some one-and-a-half centuries and not only represent a fascinating aspect of the history of medicine but which is, moreover, still ongoing at the forefront of chemical and medical discovery. Those in particular involving its major such component, l-physostigmine, have led to an understanding of some of the fundamental mechanisms occurring in physiology, pharmacology and biochemistry and, either actually or potentially (by providing a template and thereby acting as a lead compound) have provided a useful treatment for a variety of neurological disorders associated with irregularities in cholinergic transmission in which augmentation of cholinergic activity has proved to be beneficial.

• Biopharmaceutical Landscape
• Regulatory Pathways Impacting Biopharmaceuticals
• Differences in CMC Regulatory Compliance: Biopharmaceuticals Versus Chemical Drugs
• Risk Management of the Minimum CMC Regulatory Compliance Continuum
• Ever-Present Threat of Adventitious Agent Contamination
• Starting Materials for Manufacturing the Biopharmaceutical Drug Substance
• Upstream Production of the Biopharmaceutical Drug Substance
• Downstream Purification of the Biopharmaceutical Drug Substance
• Manufacturing the Biopharmaceutical Drug Product
• Complex Process-Related Impurity Profiles
• Seemingly Endless Biomolecular Structural Variants
• Indispensable Potency (Biological Activity)
• Biopharmaceutical Critical Quality Attributes
• The Art of Setting Biopharmaceutical Specifications ⁰́₃ Release and Shelf-Life
• The Challenge of Demonstrating Biopharmaceutical Product Comparability
• Strategic CMC-Focused Interactions with Regulatory Authorities

Each year for the past three years, there have been about 50 new molecular medicines approved by the United States Food & Drug Administration (FDA), of which approximately 25% were new biopharmaceuticals. Over 200 recombinant proteins, monoclonal antibodies, antibody drug conjugates, fusion proteins, and Fab fragments are now in the marketplace in both the United States of America (USA) and European Union (EU). There are also now over 60 biosimilars available for all major classes of recombinant proteins and monoclonal antibodies. In addition, gene therapies using genetically engineered viruses and genetically engineered cells are now in the marketplace, and continually growing. This degree of change is reflected in the over 400 CMC regulatory compliance references listed in this book that were either issued or updated since the release of the third edition. Deficiencies in biopharmaceutical CMC regulatory compliance rarely result in termination of a product, but in can readily cause months if not years of delay in initiating clinical trials, or advancing clinical development stages, or even market approval. In summary, this book: Updates real-world CMC deficiency examples with current examples; Addresses current FDA and EMA requirements and expectations for CMC regulatory compliance; Now includes CMC regulatory compliance for the new gene-based biopharmaceuticals

• Introduction to Ayurvedic Formulations - Exploring the Classical Concepts with Modern Science
• Scientific Approach to the Role of Turmeric in Ayurvedic Formulation and their Phytochemistry
• Ginger in Ayurvedic Preparations and its Applications in the Development of Nutraceutical, Dietary Supplements and Functional Foods and their Beneficial Effects in Various Biological Activities
• Most Modern Approach on the Phytochemistry and Therapeutic Potential of Boswellia in Ayurvedic Formulations
• Phytochemical, Botanical and Therapeutic Potential of Withania Somnifera in Ayurveda
• Scientific Evaluation on the Role of Ocimum sanctum in Ayurvedic Formulations and Their Phytochemistry and Pharmacological Activities
• Most Modern Approach on the Phytochemical Evaluation and use of Pepper Species in Ayurvedic Formulations
• Bacopa monnieri (Brahmi): Phytochemistry, Use in Traditional Ayurvedic Formulations
• Therapeutic Potential of Triphala in Ayurveda and its Phytochemical Studies
• Pharmacological Potential and Phytochemical Evaluation of Emblica Officinalis - A Wonder Herb in Ayurveda
• Galangal - The Promising Herb in Ayurvedic Formulations: Phytochemistry and Pharmacological Evaluations
• Phytochemical and Pharmacological Aspects of Cissus Quadrangularis in Ayurveda
• Ayurvedic Knowledge Inspired Approach to Modern Drug Discovery
• Ayurvedic Formulation and Their Clinical Uses
• Ayurvedic and Traditional Evidences to Clinical Trials: An Overview.
• (source: Nielsen Book Data)

Ayurvedic Medicine, or Ayurveda, is a traditional Indian health care system. Research into the medicinal plants utilised in Ayurveda is becoming a global endeavour, and large pharmaceutical companies are investing in novel drug discovery from Ayurvedic sources as a number of clinical studies have demonstrated efficacy of natural products from Ayurvedic plant extracts against common ailments such as arthritis and diabetes. Ayurvedic medicine and its components have been well described in the past, but this book represents a comprehensive source on the biochemistry and mechanisms of the pharmacological effects of natural products from Ayurvedic sources. This book is a valuable resource for researchers in natural products and alternative sources of bioactive compounds in drug discovery, as well as pharmaceutical experts and those in industry.
(source: Nielsen Book Data)

• Foreword.- Acknowledgement.- Chapter I. DEVELOPMENTS IN KNOWLEDGE OF PLANT DERIVED NATURAL PRODUCTS PHARMACOGNOSY IN THE 21ST CENTURY.- Chapter II. QUALITY REQUIREMENTS FOR HERBAL DRUGS
• ANALYTICAL METHODS.- Chapter III. BIOSYNTHESIS OF PLANT SUBSTANCES
• BIOGENETIC RELATIONSHIPS.- Chapter IV. DISCUSSION OF HERBAL DRUGS BASED ON THE BIOGENETIC CLASSIFICATION OF THEIR MAIN ACTIVE COMPONENTS.- Chapter V. BIOLOGICAL ACTIVITY OF COMPOUNDS OF PLANT ORIGIN.- Chapter VI. PLANT BIOTECHNOLOGY.- Chapter VII. APPENDIX.- Abbreviations.
• (source: Nielsen Book Data)

In the twenty-first century Pharmacognosy was transformed into a molecular science building on classic botanical and modern chemical knowledge, leading to a better understanding of the complex molecular effect - structure relationships and interactions required for the development of new drugs based on biologically active plant substances.The work demonstrates the place of phytotherapy in healing, the role of herbs in complementary and traditional therapy, and research strategies for the development of drugs of natural plant origin.This book is primarily designed for scientific researchers, but is also very useful for undergraduate and postgraduate students in their professional training. As this book discusses herbs from all over the world, it is specifically drafted to be useful not only in Hungary and Europe, but also for people in other continents as an English language encyclopaedia of medicinal plants and their biologically active compounds.
(source: Nielsen Book Data)

• Chapter 1 - An overview of G protein coupled receptors and their signaling partners
• Chapter 2 - Recent advances in orphan GPCRs research and therapeutic potential
• Chapter 3 - The Evolution of Our Understanding of GPCRs
• Chapter 4 - Approaching GPCR dimers and higher order oligomers using biophysical, biochemical and proteomic methods
• Chapter 5 - Arrestin and G protein interactions with GPCRs: a structural perspective
• Chapter 6 - GPCRs at endosomes: sorting, signaling, and recycling
• Chapter 7 - Post-translational Control of GPCR Signaling
• Chapter 8 - GPCR Signaling from Intracellular Membranes
• Chapter 9 - Ten years of GPCR structures
• Chapter 10 - Activation of class B GPCR by peptide ligands: general structural aspects
• Chapter 11 - Dynamical basis of GPCR-G-protein coupling selectivity and promiscuity
• Chapter 12 - Virtual Screening and Bioactivity Modeling for G Protein-Coupled Receptors
• Chapter 13 - Importance of structure and dynamics in the rational drug design of G protein-coupled receptor (GPCR) modulators
• Chapter 14 - Signaling, Physiology and Targeting of GPCR-Regulated Phospholipase C Enzymes
• Chapter 15 - G Protein-coupled Receptors in Metabolic Disease
• Chapter 16 - Endothelin Receptors in cerebrovascular diseases
• Chapter 17 - The calcium-sensing receptor (CaSR) in disease
• Chapter 18 - G protein-coupled receptors and their mutations in cancer - a focus on adenosine receptors
• Chapter 19 - Dopamine Receptors: Neurotherapeutic Targets for Substance Use Disorders
• Chapter 20 - PTHR1 in bone
• Chapter 21 - Activators of G-protein Signaling in the normal and diseased kidney
• Chapter 22 - Screening and characterization of GPCR-ligand interactions with mass spectrometry-based technologies
• Chapter 23 - Bioluminescence resonance energy transfer (BRET) technologies to study GPCRs
• Chapter 24 - The Application of 19F NMR to Studies of Protein Function and Drug Screening
• Chapter 25 - Chapter X: Optical Approaches for Dissecting GPCR Signaling
• Chapter 26 - GPCR Signaling in Nanodomains: Lessons from Single-Molecule Microscopy.
• (source: Nielsen Book Data)

A thorough discussion of the structure, pharmacology, function, and role of G protein-coupled receptors In GPCRs as Therapeutic Agents, distinguished researcher Dr. Annette Gilchrist delivers an authoritative and in-depth compendium of a vibrant and active area of academic and industrial drug discovery. The book serves as an important reference for new and experienced researchers studying G protein-coupled receptors and discusses the molecular pharmacology of this important target class. It also includes up-to-date material on GPCR structures and structure-based drug design. The book explores the role of GPCRs in the treatment of disease and novel approaches to their study. In addition to providing information on the structure, pharmacology, and function of GPCRs, it discusses their role in disease states, and advances new methods for measuring GPCR activity in an accessible and engaging way. The book includes: A thorough introduction to the molecular pharmacology of G protein-coupled receptors, including up-to-date material on GPCR structures and structure-based drug design In-depth discussions of the evolving pharmacology for GPCRs, intracellular trafficking, and subcellular GPCR signaling Comprehensive explorations of allosteric modulation, receptor dimerization, deorphanization, and ubiquitination Fulsome treatments of the role played by GPCRs in the treatments of cancer, substance use disorders, cerebrovascular diseases, and metabolic diseases Perfect for researchers in biochemistry, cell biology, and pharmacology, GPCRs as Therapeutic Agents will also earn a place in the libraries of professionals working in medicinal chemistry, structural biology, and clinical pharmacology.
(source: Nielsen Book Data)

• 1. Introductory overview on liposomes in food science
• 2. Vesicular delivery systems: Applications and future trends
• 3. Formation and characterization of liposome
• 4. Liposome mediated encapsulation of antimicrobials and probiotics
• 5. Liposome-assisted delivery of enzymes and proteins
• 6. Liposome for encapsulation of essential oil and fatty acids
• 7. Advances in application of liposome in dairy industries
• 8. Liposomal encapsulation of natural color, flavor and additives for food industry by liposomes
• 9. Production of supramolecular aggregates by microfluidic platforms: Applications to food industries
• 10. Stability and release of bioactives from liposome
• 11. Strategies for stabilization and preservation of liposomes
• 12. Liposomes as a biosensor in the food sector
• 13. Regulatory guidelines and protocols for food fortification and enrichment by liposomes
• 14. Liposome in food industries: Challenges and future scope.
• (source: Nielsen Book Data)

Liposomal Encapsulation in Food Science and Technology provides all the possible applications of liposomes in food and allied systems, along with recent advances made in these fields. This helps researchers in food science and technology, as well as those in interdisciplinary fields, better explore the opportunities that liposomal encapsulation offers. Among other topics, the book covers formulation and characterization of liposome, liposome mediated encapsulation of antimicrobials and probiotics, liposome-assisted delivery of enzymes and proteins, and liposome for delivery of dietary nutrients and nutraceuticals, etc. This approach facilitates building better dedicated or tandem approaches in respective fields for process/product development. Written by an international team of contributors, the book will aid academicians in developing more industry useful tools/techniques/products.
(source: Nielsen Book Data)

• From olive oil emulsions to COVID-19 Vaccines - Liposomes Came First
• Preparation of DRV liposomes
• Preparation of small unilamellar vesicles using detergent dialysis method
• Thin-film hydration followed by extrusion method for liposome preparation
• Ethanol injection method for liposome preparation
• Preparation of giant vesicles with mixed single-tail and double-tail lipids
• Scalable Liposome Synthesis by High Aspect Ratio Microfluidic Flow Focusing
• Preparation of doxorubicin liposomes by remote loading method
• Magnetic thermosensitive liposomes loaded with Doxorubicin
• Preparation and physical characterization of DNA binding cationic liposomes
• Tunable pH sensitive lipoplexes
• Solid Lipid Nanoparticles for Drug Delivery
• Stable Discoidal Bicelles – Formulation, Characterization and Functions
• The post-insertion method for the preparation of PEGylated liposomes
• Click chemistry for liposome surface modification
• Surface Modification of Liposomes Using Folic Acid
• Preparation and Characterization of Trastuzumab Fab conjugated liposomes (immunoliposomes)
• Pyrophosphorylated cholesterol modified bone-targeting liposomes formulation procedure
• Method of simultaneous analysis of liposome components using HPTLC/FID
• HPLC-MS/MS Method for Identification and Quantification of Lipids in Liposomes
• DPH probe method for liposome-membrane fluidity determination
• Imaging of Liposomes by Negative Staining Transmission Electron Microscopy and Cryogenic Transmission Electron Microscopy
• Visualization and characterization of liposomes by Atomic Force Microscopy (AFM)
• Determination of the sub-cellular distribution of fluorescently labeled liposomes using confocal microscopy
• Liposome biodistribution via europium complexes
• Quantification of a fluorescent lipid DOPE-NBD by an HPLC method in biological tissue: application to study liposome’s uptake by human placenta.

This third edition provides new and updated chapters detailing preparation of liposomes, physicochemical characterization of liposomes, lipid analysis, drug encapsulation, surface modification, stimuli response as well as cellular interaction, and biodistribution. Also included is an updated chapter on the history and evolution of the field of liposomology. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Liposomes: Methods and Protocols, Third Edition aims to serve as a reference for graduate students, post-doctoral researchers as well as established investigators utilizing lipid-based systems.

• Introduction/Overview
• Target analysis of synthetic cannabinoids in blood and urine
• Target analysis of synthetic cathinones in blood and urine
• Target analysis of phenethylamines, piperazines and tryptamines in blood and urine
• Target analysis of synthetic opioids in blood and urine
• Target analysis of synthetic benzodiazepines in blood and urine
• Target analysis of NPS in alternative matrix hair
• Target analysis of NPS in alternative matrix oral fluid
• Target analysis of NPS in other alternative matrices (dried blood spots, meconium)
• Target analysis of NPS in postmortem samples
• High Resolution Mass Spectrometry in NPS qualitative analysis
• High Resolution Mass Spectrometry in NPS quantitative analysis
• High Resolution Mass Spectrometry in identification of new analytes & metabolites
• Alternative NPS screening approaches for high-throughput laboratories.

This collection provides detailed information on current advances in analytical methods and strategies employed for monitoring and discovering a wide range of novel psychoactive substances (NPS) in clinical and forensic laboratories. The main classes of NPS in terms of prevalence include synthetic cannabinoids, synthetic cathinones, synthetic opioids, and designer or synthetic benzodiazepines, and this book explores selecting the appropriate sample matrix and analytical testing approaches for laboratories faced with NPS drug testing, such as in blood, urine, saliva, and hair. Written for the Methods in Pharmacology and Toxicology series, chapters in this volume feature the kind of detailed implementation advice from the experts that leads to successful results in the lab. Authoritative and practical, Methods for Novel Psychoactive Substance Analysis serves as an ideal guide for forensic and clinical toxicologists, pharmacologists and chemists in academic and research settings, as well as for private laboratories seeking to increase our ability to test for these substances.

• 1. Traditional Applications of Magnetic Nanoparticles in Clinical Diagnostic and Therapeutics.-
• 2. Modern Biomedical Applications of Magnetic Nanoparticles.-
• 3. Concluding Remarks and Future Perspectives.
• (source: Nielsen Book Data)

This book provides a comprehensive insight into the current research trends and ongoing advances in biomedical applications of magnetic nanoparticles. New uses for magnetic nanoparticles in biomedical fields such as magnetic particle imaging, microfluidics applications, organelle isolation, nanovaccines, and magnetogenetics are presented in keeping with traditional applications of magnetic nanoparticles in clinical diagnostics and therapeutics. Each section of the book provides feature questions with answers available from various research showcases and literature references, together with numerous illustrations to help readers grasp key ideas. The book was written for graduate students and researchers in the fields of magnetic nanomedicine and nanobiotechnology. .
(source: Nielsen Book Data)

• 1. Conducting polymers as drug release systems
• 2. Electrospinning for drug delivery applications
• 3. Melt-electrospinning and electrowriting for pharmaceutical and biomedical applications
• 4. Pharmaceutical Spray Drying
• 5. Vat photopolymerization 3D printing for drug delivery applications
• 6. Semi-solid extrusion 3D printing for the development of dosage forms for special patient groups
• 7. Binder-Jetting Powder bed 3Dprinting for the fabrication of drug delivery systems
• 8. 3D printing for localized cancer therapy
• 9. 4D Printing in Pharmaceutics & Biomedical Applications
• 10. Lithography in Drug-Delivery
• 11. Micro-moulding and its application to drug delivery
• 12. Supercritical Fluids: A Promising Technique in Pharmaceutics
• 13. Microfluidics as a tool for the synthesis of advanced drug delivery systems
• 14. Nanofluidic Technologies for Drug Screening and Drug Delivery
• 15. Nanoparticles at the stage of clinical trials
• 16. Nasal drug delivery systems for the treatment of diseases of the central nervous system and tuberculosis
• 17. Regulatory aspects and barriers in using ground-breaking technologies. .

New materials and manufacturing techniques are evolving with the potential to address the challenges associated with the manufacture of medicinal products that will teach new tricks to old drugs. Nano- and microfabrication techniques include manufacturing methods such as additive manufacturing, lithography, micro-moulding, spray drying, and supercritical fluids among many others. The increasing resolution of new techniques allow researchers to produce objects with micrometric resolutions. This book follows a consecutive order, beginning with a background in the current field and limitations in the manufacturing of different pharmaceutical products, moving on the classification of each method by providing recent examples, and future prospective on a variety of traditional and new Nano and microfabrication techniques. A focus on the materials used to prepare these systems and their biocompatibility, including applied topics such as clinical applications and regulatory aspects also covered, offering the reader a holistic view of this rapidly growing field.

• Chapter 1_Introduction to Lung diseases. -Chapter 2_Natural polymers for drug delivery. -Chapter 3_Drug delivery based on various natural polymers for lung diseases. -Chapter 4_Plant-derived natural polymers employed in respiratory diseases. -Chapter 4.1_Cellulose-based drug delivery systems. -Chapter 4.2_Pectin derived drug delivery systems. -Chapter 4.3_Starch-based drug delivery systems. - Chapter 4.4_Cyclodextrin derived drug delivery systems. - Chapter 4.5_Gum-based drug delivery systems. - Chapter 4.6_Glucomannan and xyloglucan derived drug delivery systems. - Chapter 4.7_Arabinogalactan, latex based drug delivery systems. - Chapter 5_Animal-derived natural polymers employed in respiratory diseases. - Chapter 5.1_Chitosan-based drug delivery systems for respiratory diseases. - Chapter 5.2_ Albumin for application in DDS for lung diseases. - Chapter 5.3_Gelatin in DDS for treatment of lung disorders. - Chapter 5.4_Hyalouronan and chondroitin sulphate-based drug delivery systems. - Chapter 5.5_Insulin-based drug delivery systems. - Chapter 6_Microorganisms derived natural polymers employed in respiratory diseases. - Chapter 6.1_Xanthan gum-based drug delivery systems for respiratory diseases. - Chapter 6.2_Dextran for application in DDS for lung diseases. - Chapter 6.3_Pullulan in DDS for treatment of lung disorders. - Chapter 7_Algae derived natural polymers employed in respiratory diseases. - Chapter 7.1_Alginate based drug delivery systems for respiratory disease. -Chapter 7.2_Carrageenan based drug delivery systems for respiratory disease. -Chapter 7.3_Agar based drug delivery systems for respiratory disease. -Chapter 8_Clinical trails and Regulatory issues of natural polymers employed in respiratory diseases. -Chapter 9_Challenges of natural polymers-based drug delivery systems in combating lung diseases. -Chapter 10_Future prospects of natural polymers-based drug delivery systems in combating lung diseases.
• .
• (source: Nielsen Book Data)

This book comprehensively reviews the recent developments of natural polymers for drug delivery systems in various lung disorders. The initial chapter provides a brief introduction to lung diseases with a focus on the current landscape of natural polymers and trends in understanding the disease pathology. Several chapters of the book devoted to the latest technologies and advances in drug delivery systems include practical solutions on designing more effective drug delivery systems based on natural polymers that can be used in the management of lung diseases. Further, the book presents biodegradable and bio-reducible- natural polymers- based drug delivery systems for lung diseases. Towards the end, the book examines future prospects and challenges of natural polymers-based drug delivery systems in combating lung diseases. This book is useful for phytochemists, formulation/drug delivery, biological and translational researchers and clinicians working in the field of lung disorders.
(source: Nielsen Book Data)

• Section I. Introduction 1. Why is this topic important? 2. Source, fate and transport of ENMs in the environment, especially those that may eventually reach plant systems.
• Section II Biogeochemical cycle of ENMs before plant exposure explained at the molecular level 3. Biophysicochemical transformations of ENMs in soil 4. Biophysicochemical transformations of ENMs in water 5. Biophysicochemical transformations of ENMs in air
• Section III Molecular interaction of ENMs and plants: Reactions and mechanisms 6. Biophysicochemical transformation of ENMs at the root level 7. Chemical reactions and mechanisms of ENMs transport in plants 8. Biotransformation of ENMs in leaves 9. ENMs and plants: Are the reaction products more or less toxic? 10. Biodegradation of plants laden with ENMs.
• (source: Nielsen Book Data)

Physicochemical Interactions of Engineered Nanoparticles and Plants: A Systemic Approach, Volume Four in the Nanomaterial-Plant Interactions series, presents foundational information on how ENMs interact with the surrounding environment. Key themes include source, fate and transport of ENMs in the environment, biophysicochemical transformations of ENMs, and chemical reactions and mechanisms of ENMs transport in plants. This book is an essential read for any scientist or researcher looking to understand the molecular interactions between ENMs and Plants. Engineered nanomaterials (ENMs) reach plant ecosystems through intentional or unintentional pathways. In any case, after release, these materials may be transformed in the environment by physical, chemical and biochemical processes. Once in contact with plant systems, biotransformation may still occur, affecting or stimulating plant metabolism. Since plants are the producers to the food chain, it is of paramount importance to understand these mechanisms at the molecular level.
(source: Nielsen Book Data)

• SECTION 1: Nanomaterials applied to phytochemicals 1.Phytochemicals as potential biopharmaceutical agents 2.Diseases with the highest mortality 3.Nanomaterials 4.Methods of nanoencapsulation of phytochemicals using organic platforms 5.Administration of phytochemical nanoformulations (main routes of drug delivery)
• SECTION 2: Phytochemicals and nanotechnology 6.Nanoformulations applied to the delivery of terpenes 7.Nanoformulations applied to the delivery of alkaloids 8.Nanoformulations applied to the delivery of phenolic compound 9.Nanoformulations applied to the delivery of sulforaphane 10.Perspectives.
• (source: Nielsen Book Data)

Phytochemical Nanodelivery Systems as Potential Biopharmaceuticals comprehensively reviews current information on nanotechnology applied to phytochemical nanoencapsulation to enhance their bioavailability and bioactivity. The book is divided into two sections, the first section critically reviews current information on the field of nanotechnology and phytochemicals, and the second section highlights the pre-clinical and clinical studies of phytochemicals to comprehensively review the efficacy of these molecules as drugs of human use. Phytochemical Nanodelivery Systems as Potential Biopharmaceuticals provides a useful overview of this rapidly evolving field for materials scientists and pharmaceutical scientists, as well as for those with an interest in biopharmaceuticals from plant sources, such as organic chemists and food scientists.
(source: Nielsen Book Data)