%{search_type} search results

• Gustation in Drosophila melanogaster / Matthew Cobb, Kristin Scott, Michael Pankratz
• Drosophila Gr5a: expression pattern, ligand profile and transduction pathway / Sylwester Chyb
• Neurophysiology of gustatory receptor neurones in Drosophila / Teiichi Tanimura ...[et al.]
• Chemosensory regulation of feeding in the blowfly: several studies after 'The hungry fly' / Mamiko Ozaki, Tadashi Nakamura
• Tasting in plant-feeding insects: from single compounds to complex natural stimuli / Joop J.A. van Loon ... [et al.]
• Tasting toxicants as bitter: phytoecdysteroids / Frédéric Marion-Poll ... [et al.]
• Peripheral modulation of taste responses / Hansjürgen Schuppe, Philip L. Newland
• The 'sweet tooth' of the honeybee: the perception of nectar and its influence on honeybee behaviour / Geraldine A. Wright
• Effects of experience on the physiology of taste discrimination in insects / Marta L. del Campo, Carol I. Miles, Marina C. Caillaud
• Evolutionary biology of learning in insects: the search for food / Frédéric Mery.

This SEB book will have chapters covering different approaches to taste research including genes and receptors, taste coding in the periphery and its modulation, taste coding in the central nervous system and behaviour, and nutrition and nutritional regulation.
(source: Nielsen Book Data)

• 1. What can we learn from the cross-species biology of ageing?
• 2. Rebirth and death: Nitric oxide and reactive oxygen species in seeds
• 3. Ageing and oxidants in the nematode Caenorhabditis elegans
• 4. The perception of reactive oxygen species in plants: the road to signal transduction
• 5. Mechanisms and genes controlling programmed cell death and Darwinian fitness in plants
• 6. Ageing research in the post-genome era: New technologies for an old problem
• 7. Telomeres, ageing and oxidation
• 8. A-type lamins, disease and ageing: A stress-induced relationship?
• 9. Role of the glyoxalase pathway in delaying plant senescence under stress conditions
• 10. Catalase regulation during leaf senescence of Arabidopsis
• 11. Atmospheric CO2 signalling, cellular redox state and plant growth and development
• 12. Protein damage in the ageing process: Advances in quantitation and the importance of enzymatic defences.
• (source: Nielsen Book Data)

This SEB volume will address recent issues in ageing research, particularly the roles of accumulating damage to protein and nucleotides in aging and nutritional and prospective interventions to slow the ageing process.
(source: Nielsen Book Data)

• Preface
• 1. Modelling Neurodegenerative Diseases in "Drosophila"
• 2. "Drosophila" Genetics for the Analysis of Neurobiological Disease
• 3. Using "Drosophila "Models to Unravel Pathogenic Mechanisms That Underlie Neurodegeneration in Tauopathies
• 4. Modelling Cell and Isoform Type Specificity of Tauopathies in "Drosophila"
• 5. Using a "Drosophila "Model of Alzheimer's Disease
• 6. Amyloid Peptides and Ion Channel Function in "Drosophila" Models of Alzheimer's Disease
• 7. Genetic Models of Parkinson's Disease: Mechanisms and Therapies
• 8. Modelling Lyosomal Storage Disease in "Drosophila
• "9. "Drosophila melanogaster "in the Study of Epilepsy
• 10. Hereditary Spastic Paraplegia Genes in "Drosophila": Dissecting Their Roles in Axonal Degeneration and Intracellular Traffic
• 11. Triplet Repeat Diseases - Role of Fly Models in Understanding Disease Mechanisms and Designing Possible Therapies.
• (source: Nielsen Book Data)

"Drosophila "gives an overview of the ways in which Drosophila is currently being used as a model organism to further our understanding of a spectrum of human neurological diseases. Each chapter is written by respected researchers and gives an excellent account of the subject that is suitable for postgraduate and postdoctoral researchers.
(source: Nielsen Book Data)

• 1. Plant D-Type Cyclins: Structure, Roles and Functions
• 2. Initiation of DNA Replication
• 3. Mcm10 and DNA Replication in Fission Yeast
• 4. Copying the Template - With A Little Help From My Friends?
• 5. G2/M Transition in Eukaryotes
• 6. Many Faces of Separase Regulation
• 7. The Centrosome in the Eukaryotic Cell
• 8. Division Versus Differentiation in the Early "Xenopus" Embryo
• 9. Endoreduplication Control During Plant Development
• 10. Chromatin Modifications and Nucleotide Excision Repair
• 11. DNA Ligase - A Means to an End Joining
• 12. Cell Cycle Checkpoint-Guarded Routes to Catenation-Induced Chromosomal Instability
• 13. The Spindle Checkpoint: How Do Cells Delay Anaphase Onset?
• 14. A Mechanism Coupling Cell Division and the Control of Apoptosis
• 15. The Cytoskeleton and the Control of Organelle Dynamics in the Apoptotic Execution Phase.
• (source: Nielsen Book Data)

"The Eukaryotic Cell Cycle" gives an overview of the stages of the eukaryotic cell cycle, as well as discussing important experiments, research, organisms of interest and findings connected to each stage of the cycle and the components involved in these. This volume, written by respected researchers, gives an excellent account of the eukaryotic cell cycle that is suitable for graduate and postdoctoral researchers.
(source: Nielsen Book Data)

• Bioinformatic approaches to biological systems / David R. Westhead, Iain W. Manfield, Christopher J. Needham
• Cell sampling and global nucleic acid amplification / Vigdis Nygaard, Eivind Hovig
• Methods of proteome analysis: challenges and opportunities / Sarah R. Hart and Simon J. Gaskell
• Vertical systems biology: from DNA to flux and back / Annamaria Bevilacqua ... [et al.]
• Using mathematical models to probe dynamic expression data / Nick Monk
• Gene regulatory network models: a dynamic and integrative approach to development / Elena R. Alvarez-Buylla ... [et al.]
• Spatio-temporal dynamics of protein modification cascades / Boris N. Kholodenko and Herbert M. Sauro
• Intracellular signalling during bacterial chemotaxis / Marcus J. Tindall ... [et al.]
• Modelling the mammalian heart / Richard Clayton and Martyn Nash
• Modelling root growth and development / Eric M. Kramer, Xavier Draye, Malcolm J. Bennett.

Systems biology is the study of organisms as interacting networks of genes, proteins and reactions. "Practical Systems Biology" provides a detailed overview of the different approaches used in this relatively new discipline, integrating bioinformatics, genomics, proteomics and metabolomics. Various areas of research are also discussed, including the use of computational models of biological processes, and post-genomic research. Each chapter is written by an experienced researcher and gives an excellent account of various issues of systems biology that is suitable for postgraduate and postdoctoral researchers who are interested in this expanding area of science.
(source: Nielsen Book Data)

• Comparative genomics and drug discovery in trypanosomatids
• The practical implications of comparative kinetoplastid genomics
• The relevance of host genes in malaria
• Nicotinic acetylcholine receptors as drug/chemical targets, contributions from comparative genomics, forward and reverse genetics
• Discovery of novel sodium channel inhibitors : a gene family-based approach
• 'Omics' in translational medicine : are they lost in translation?
• Drug-target discovery in silico : using the Web to identify novel molecular targets for drug action.

"Comparative Genomics and Proteomics in Drug Discovery" gives an overview of how emerging genomic and proteomic technologies are making significant contributions to global drug discovery programmes, and in particular the key role that comparative genomics and proteomics play within this strategy. Each chapter is written by respected authorities, with hands-on experience, from both academic and pharmaceutical backgrounds.
(source: Nielsen Book Data)

• Ch
• 1. Introduction. Part I: Fundamental Processes in Host-Parasite Relationships. Ch
• 2. Immunity in the host-parasite relationships of fishes. Ch
• 3. Physiological stress and disease resistance in fishes. Ch
• 4. The role of apoptosis in non-mammalian host-parasite relationships. Ch
• 5. Necrosis and the host-parasite relationship. Ch
• 6. Immunostimulation targeted at the host-parasite level. Part II: Selected Host-Parasite Relationships. Ch
• 7. Pathophysiology in piscine and mammalian haemoflagellate diseases. Ch
• 8. Avian coccidiosis: a disturbed host-parasite relationship. Ch
• 9. Comparative aspects of the tick host relationship: immunobiology, genomics, and proteomics. Ch
• 10. Host-parasite interactions of sea lice: current state of knowledge and insights from other host-parasite relationships. Ch
• 11. Conclusions.
• (source: Nielsen Book Data)

This volume summarizes current research into the physiology and molecular biology of host-parasite interactions. Brought together by leading international experts in the field, the first section outlines fundamental processes, followed by specific examples in the concluding section. Covering a wide range of organisms, Host-Parasite Interactions is essential reading for researchers in the field.
(source: Nielsen Book Data)

• 1) The Nuclear Envelope
• A Comparative Overview David E. Evans, John A. Bryant and Chris Hutchison 2) The Nuclear Envelope Proteome Mathias Dreger and Henning Otto 3) Nuclear Envelope Proteins and Human Disease Howard J. Worman 4) Protein Interactions, Right or Wrong, in Emery-Dreifuss Muscular Dystrophy Glenn E. Morris 5) Plant Nuclear Envelope Proteins Annkatrin Rose, Shalaka Patel and Iris Meier 6) Structure, Function and Assembly of the Nuclear Pore Complex Sheona Drummond and Terry Allen 7) Import and Export at the Nuclear Envelope Martin Goldberg 8) Regulating Gene Expression in Mammalian Cells: How Nuclear Architecture Influences mRNA Synthesis and Export to the Cytoplasm Dean A. Jackson 9) Nuclear Shuttling in Plant Cells Sondra G. Lazarowitz, Roisin C. McGarry, Yoshimi D. Barron and Miguel F. Carvalho 10) Dynamics of Nuclear Lamina Assembly and Disassembly Jos L. V. Broers and Frans C. S. Ramaekers 11) Spatial and Temporal Control of Nuclear Envelope Assembly by Ran GTPasePaul R. Clarke and Chuanmao Zhang 12) Nuclear Envelope Dynamics During Mitosis Brian Burke, Melissa Crisp and Davide Salina 13) Nuclear Dynamics in Higher Plants David W. Galbraith 14) The Nuclear Envelope in the Plant Cell Cycle David E. Evans, Sarah Irons, Mekdes H. Debela and Federica Brandizzi.
• (source: Nielsen Book Data)

The Nuclear Envelope brings together the major current topics in nuclear envelope structure, transport, transcriptional regulation and cell signaling. The volume is divided into four sections: 1. Proteins of the nuclear envelope, including nuclear envelope proteomics, structure and function. 2. Nuclear pores and transport at the nuclear envelope, including pore complex structure, assembly and function and import and export pathways. 3. Nuclear envelope dynamics, including dynamics of lamina assembly and disassembly. 4. Nuclear signalling and transcription regulation, including signalling to the nucleus and spectrin repeat proteins and their implications or communication between the nucleus and cytoplasm.
(source: Nielsen Book Data)

• Ch
• 1. DRINKING IN HAGFISHES AND LAMPREYS, J.C. Rankin. The evolution of vertebrate osmoregulation. Drinking in hagfishes. Drinking in lampreys. Materials and Methods. Ch
• 2. THE CONTROL OF DRINKING IN ELASMOBRANCH FISH WITH SPECIAL REFERENCE TO THE RENIN-ANGIOTENSIN SYSTEM, W.G. Anderson, A. Wells. Y. Takei and N. Hazon. Introduction. Regulation of salt and water balance. The rennin-angiotensin system-comparative aspects. Control of drinking in elasmobranches. Control of drinking and osmotic balance. Ch
• 3. DRINKING IN (VERY YOUNG) FISH, G Flick, S. Varsamos, P.M.G. Guerreiro, X. Fuentes, M.O. Huising and J.C. Fenwick. Introduction. The onset of drinking. Calciotropic hormones and drinking in fish. Drinking hormones and antigens. Ch
• 4. WATER TRANSPORT AND AQUAPORINS IN THE EUROPEAN EEL, J-H. Lignot, C.P. Cutler, N. Hazon and G. Cramb. Introduction. Water transport in fish. Facilitated water transporters (aquaporins). Aquaporins in fish. Possible roles for AQP1 and AQP3 in the digestive tract of eels. Ch
• 5. HORMONAL CONTROL OF DRINKING IN EELS: AN EVOLUTIONARY APPROACH, Y. Takei. Introduction. Mechanisms regulating drinking in vertebrates. Renin-angiotensin system (RAS). Natriuretic peptide system (NPS). Kallikrein-kinin system (KKS). Evolutionary consideration. Ch
• 6. THE ROLE OF ARGININE VASOTOCIN IN TELEOST FISH OSMOREGULATION, J. Warne. Introduction. Response of the AVT system to salinity challenge. Actions of AVT at target tissues. Ch
• 7. FACILITATIVE EFFECTS OF ANGIOTENSIN II ON PROLACTIN CELL RESPONSES TO OSMOTIC STIMULATION IN TILAPIA, T. Hirano, T.A. Leedom, A.P. Seale and E.G Grau. Introduction. Effects of blood withdrawal on plasma PRL levels. Effects of ANG II on PRL secretion. Facilitation of PRL cell responses to osmotic stimulation by ANG II. Ch
• 8. NEPHRON STRUCTURE AND IMMUNOHISTOCHEMICAL LOCALIZATION OF ION PUMPS AND AQUAPORINS IN THE KIDNEY OF FROGS INHABITING DIFFERENT ENVIRONMENTS, M. Uchiyama and H. Yoshizawa. Introduction. Materials and Methods. Morphology of anuran kidney. Na+, K+-ATPase. H+-ATPase. H+, K+-ATPase. Aquaporins. Ch
• 9. SODIUM AND WATER TRANSPORT AND URINE CONCENTRATION IN AVIAN KIDNEY, H. Nishimura and Z. Fan. Introduction. Functional morphology of the loop of Henle. NaCl and water transport in the loop of Henle. Water transport in the collecting duct. Countercurrent multiplier mechanism for urine concentration. Aquaporin water channels. Ch
• 10. CONTROL OF WATER BALANCE IN MAMMALS, R.J. Balment. Introduction. Renal mechanisms supporting water balance. Thirst and compensatory drinking. Integration of regulatory mechanisms. Integration of central and peripheral mechanisms to maintain water balance. Ch
• 11. ORGANISMAL HANDLING OF WATER BALANCE IN VERTEBRATES, R. Acher and J. Chauvet. Introduction. The primordial osmoregulation in prokaryotic and e.
• (source: Nielsen Book Data)

Osmoregulation and Drinking in Vertebrates presents some of the most exciting recent advances in the area of osmoregulation, from the control of gene expression to whole animal response. In particular, the differences and similarities in the drinking response between a number of vertebrate groups including both aquatic and terrestrial organisms. As such, this volume will be of interest to all those working in the fields of marine and freshwater biology, comparative physiology and endocrinology and molecular biology of ion transporters and water channels.
(source: Nielsen Book Data)

• Neural stem cells of the mammalian forebrain
• similarity and differences between the haemopoietic and brain stem cell system
• lineage selection and isolation of neural precursors from embryonic stem cells
• early generated Cajal-Retzius cells have different functions in cortical development
• signalling cascade of CNR cadherins (Reelin receptors) in the mammalian brain
• the role of the Reelin pathway in cortical development
• the "Drosophila" nervous system as a model for assymetric cell division
• developmental abnormalities in early-onset hydrocephalus - clues to signaling
• stem cells and regeneration in invertebrate deuterostomes.
• (source: Nielsen Book Data)

Brain Stem Cells provides a detailed analysis of the mechanisms which underline both the neuronal and cortical development of the brain. Recent studies have led to the identification and characterisation of brain stem cells and it is now clear that these cells continue to develop throughout adult life. This raises the prospect of treating brain-damaged patients with neurons cultured from their own stem cells. Written by leading experts in the field, this book will be essential reading for all those with an interest in this fast-developing area.
(source: Nielsen Book Data)

• APOPTOPIC CELL DEATH: FROM WORMS TO WOMBATS BUT WHAT ABOUT THE WEEDS?. The molecular mechanisms of programmed cell death in caenorhabditis elegans. Comparison with mammalian apoptosis. Plants, from arabidopsis to zinnia. General conclusions. CASPASES - AT THE CUTTING EDGE OF CELL DEATH. Introduction. Caspases and their properties. Structure of the caspases. Activation and regulation of the caspases. Evolution of the caspases. MODULATION OF DEATH RECEPTOR SIGNALLING.Introduction. Death receptors and apoptosis. Activation of death receptors by death ligands. Decoy receptors. Inhibition of death receptor by FLIP. Conclusion. THE ROLES OF THE BCL-2 FAMILY IN THE MODULATION OF APOPTOSIS. Introduction. Bcl-2 family: life or death promoters. Function of the Bcl-2 family proteins. Cellular control of the Bcl-2 family proteins. Over-expression of Bcl-2 family proteins and chemoresistance. Drug resistance in B-CLL. Strategies for inhibiting Bcl-2 function in B-CLL. Conclusions. THE ROLE OF GRANZYMES AND SERPINS IN REGULATING CELL GROWTH AND DEATH. Introduction. Introduction of apoptosis by cytotoxic T cells and natural killer cells. How does granzyme B gain access to the interior of target cells. Molecular targets of granzyme B. Regulation of granzyme B by PI
• -9. The roles of intracellular serpins in cell growth and death. Conclusions. MITOCHINDRIA AND CELL DEATH: A PORE WAY TO DIE? Introduction. The mitochondrial permeability transition. Mitochondria and apoptosis. REGULATION OF APOPTOSIS BY CELL METABOLISM, CYTOCHROME C AND THE CYTOSKELETON. Introduction Apoptosis: the general scene. Apoptosis the cytoskeleton. Apoptosis and metabolism. Measurement of apoptosis. Apoptosis in a defined haematopoietic cell system. IL3 dependency: a universal model for life/death signalling. Final comments. ORGANELLES-SPECIFIC DEATH PATHWAYS. Introduction Bcl-2 family proteins are present on multiple subcellular compartments. ER dysfunction induces apoptosis. Apoptosis initiated at other intracellular locations. The role of subcellular apoptotic complexes. Concluding remarks. TELOMERES, TELOMERASE AND CELLUAR IMMORTILIZAITON. Introduction. Cellular or replicative senescence. Telomeres: form and function. Telomere-binding proteins. Telomerase. Telomerase and cancer. Telomerase-knockout mouse. Immortilization of normal cells by telomerase. Future prospects. BACK FROM THE BRINK: PLANT SENESCENCE AND ITS REVERSIBILITY. Many ways to get dead. Organ senescence has a cellular basis. How do senescing cells change colour?. Senescence is an energy- demanding oxidative process. Proteins are remobilized in cell senescence - but how?. Senescence is programmed. Senescence is regulated at the transcriptional and post-transcriptional level. Senescence is reversible. Post-mortem. SENESCENCE AND CELL DEATH IN BRASSIUCA NAPUS AND ARABIDOPSIS. What is senescence in plants? Senescence and programmed cell death. When i.
• (source: Nielsen Book Data)

This title, the 52nd in symposium series, presents a comprehensive review of apoptosis and features contributions from many internationally recognised authors. The book is the first to integrate programmed cell death in plants, invertebrates and vertebrates. Rapid publication ensures that the very latest research is included.
(source: Nielsen Book Data)

• Ch 1. Microcollinearity and segmental duplication in the evolution of grass nuclear genomes--
• Ch 2. Sequencing and mapping the arabidopsis genome: a weed model for real crops--
• Ch 3. Rice cDNAs as a model for expressed genes of plants--
• Ch 4.
• (source: Nielsen Book Data)

Focusing on the comparison of genomes of different species, this symposium highlighted the common elements of genome organization which are present in genera, families or even kingdoms, and explored aspects of the higher-order structure, evolution, variation and organization of the whole plant genome and its components. The contributors to this work include those involved in the major genome projects, such as those for rice and Arabidopsis, as well as species of practical importance, such as timber pines and wheat, species with genomes which were often regarded as intractable to analysis.
(source: Nielsen Book Data)

• Molecular biology of muscle cell differentiation. Eclipse of the identifiable myoblast
• Regulating the myogenic regulators
• The consequences of a constitutive expressions of MyoD1 in ES cells and mouse embryos
• Regulation of myogenin expression in normal and transformed myogenic cell lines
• Inhibition of in vitro muscle differentiation by the immortalizing oncogene Py Lt-ag
• A cell division counter exists in the chick embryo myogenic lineage
• Multimeric structures influence the binding [activity] of bHLH muscle regulatory factors
• Isolation and functional comparison of Dmyd, the Drosophila homologue of the vertebrate myogenic determination genes, with CMD1.

• Comparative Muscle Genes. Drosophila actin mutants and the study of myofibrillar assembly and function
• Expression of actin isoforms in Artemia
• Switches in fish myosin genes induced by environment temperature in muscle of the carp
• Regulation of muscle gene expression in crustacea over the moult cycle
• cDNA cloning and sequence comparisons of human and chicken muscle C-protein and 86 kD protein
• Multiple products of the Duchenne muscular dystrophy gene
• The role of the skeletal muscle ryanodine receptor gene in malignant hyperthermia.

• Molecular biology of muscle development. Expression of muscle genes in the mouse embryo
• Molecular analysis of protein sorting during biogenesis of muscle cytoarchitecture
• Cardiac troponin T gene expression in muscle
• Gene expression during cardiac development
• Regulation of myosin heavy chain and actin isogenes during cardiac growth and hypertrophy
• Carbonic anhydrase 3(CA3), a mesodermal marker
• A molecular approach towards the understanding of early heart development : an emerging synthesis.

• Transcriptional control of muscle genes. Reciprocal changes in myosin isoform expression in rabbit fast skeletal muscle resulting from the application and removal of chronic electrical stimulation
• Fast-to-slow transition in myosin heavy chain expression of rabbit muscle fibres induced by chronic low-frequency stimulation
• Regulation of insulin-like growth factor 1 gene expression in skeletal muscle
• Activation of muscle-specific transcription by myogenic helix-loop-helix proteins
• Positive and negative gene regulation in muscle
• CIS regulating elements which control in vivo alternative splicing of the chicken β tropomyosin primary transcript
• RNA of chick embryonic muscle : cloning and sequence of subspecies which is antisense RNA.

The 56th annual Cold Spring Harbor Symposium in June 1991, saw presentations from some 90 investigators on DNA replication, mitosis, cell cycle controls, check points affecting cycling, and transcriptional control.
(source: Nielsen Book Data)